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Year : 2015  |  Volume : 40  |  Issue : 3  |  Page : 148-149

Factor XIII deficiency: the first case reported from Nepal

1 Department of Internal Medicine, Civil Service Hospital, Kathmandu, Nepal
2 Department of Anaesthesiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Correspondence Address:
Gentle S Shrestha
Department of Anaesthesiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1110-1067.164742

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The initial hemostatic plug is not sufficient to prevent blood loss unless it is stabilized by the action of plasma factor XIII. Congenital or acquired factor XIII deficiency must be considered when a patient has a major bleeding disorder and all of the initial screening laboratory tests are normal, including prothrombin time, activated partial thromboplastin time, platelet count, and bleeding time. Here we report the case of a child with congenital factor XIII deficiency, who presented with bleeding from umbilical stump and spontaneous hematoma in the left buttock.

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