Close
  Indian J Med Microbiol
 

Figure 3: Gel electrophoresis showed digestion of PCR product at exon 7 by MwoI restriction endonuclease. Lanes 1, 2, and 4– 6 showed wild TPMT*1/*1. Lanes 3 and 7 showed heterozygous mutation of 460G > A at exon 7. Lane 8 showed 100 bp DNA ladder. TPMT, thiopurine S-methyltransferase.

Figure 3: Gel electrophoresis showed digestion of PCR product at exon 7 by <i>Mwo</i>I restriction endonuclease. Lanes 1, 2, and 4– 6 showed wild <i>TPMT*1/*1</i>. Lanes 3 and 7 showed heterozygous mutation of 460G > A at exon 7. Lane 8 showed 100 bp DNA ladder. <i>TPMT</i>, thiopurine <i>S</i>-methyltransferase.